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1

Antiviral Pathway Activation in Chronic Fatigue Syndrome and Acute Infection

De Meirleir, Kenny, Suhadolnik, Robert J., Lebleu, Bernard, Englebienne, Patrick

Journal:

Clinical Infectious Diseases

Year:

2002

Language:

english

File:

PDF, 55 KB

english, 2002

2

Dynamics of detachment of Escherichia coli from plasma-mediated coatings under shear flow

Mercier-Bonin, Muriel, Duviau, Marie-Pierre, Ellero, Christophe, Lebleu, Nathalie, Raynaud, Patrice, Despax, Bernard, Schmitz, Philippe

Journal:

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

3

Assessment of High-Affinity Hybridization, RNase H Cleavage, and Covalent Linkage in Translation Arrest by Antisense Oligonucleotides

GEE, JAY E., ROBBINS, IAN, VAN DER LAAN, ALEXANDER C., VAN BOOM, JACQUES H., COLOMBIER, CAROLINE, LENG, MARC, RAIBLE, ANNETTE M., NELSON, JEFFREY S., LEBLEU, BERNARD

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1998

Language:

english

File:

PDF, 10.78 MB

english, 1998

4

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Marita Overhoff, Martina Alken, Rosel Kretschmer-Kazemi Far, Marc Lemaitre, Bernard Lebleu, Georg Sczakiel, Ian Robbins

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

5

Modulation of nucleic acid information processing by PNAs: potential use in anti-viral therapeutics

Lionel Bastide, Bernard Lebleu, Ian Robbins

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 284 KB

english, 2003

6

DNA protein interactions at the interferon-responsive promoter elements: potential for an H-DNA conformation

Roy, Christian, Lebleu, Bernard

Journal:

Nucleic Acids Research

Year:

1991

Language:

english

File:

PDF, 7.36 MB

english, 1991

7

Antisense inhibitors of HIV: Problems and perspectives

Geneviève Degols, Jean-Paul Leonetti, Pierre Milhaud, Nadir Mechti, Bernard Lebleu

Journal:

Antiviral Research

Year:

1992

Language:

english

File:

PDF, 553 KB

english, 1992

8

Oligonucleotide-poly(L-lysine)-heparin complexes: Potent sequence-specific inhibitors of HIV-1 infection

Degols, Genevieve, Devaux, Christian, Lebleu, Bernard

Journal:

Bioconjugate Chemistry

Year:

1994

Language:

english

File:

PDF, 1.27 MB

english, 1994

9

pH-Sensitive Liposomes and Antisense Oligonucleotide Delivery

Milhaud, Pierre G., Bongartz, Jean Pierre, Lebleu, Bernard, Philippot, Jean R.

Journal:

Year:

1996

Language:

english

File:

PDF, 708 KB

english, 1996

10

α-DNA VI: comparative study of α- and β-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition

Gagnor, Corinne, Bertrand, Jean-Remy, Thenet, Sophie, Lemaître, Marc, Morvan, François, Rayner, Bernard, Malvy, Claude, Lebleu, Bernard, Imbach, Jean-Louis, Paoletti, Claude

Journal:

Nucleic Acids Research

Year:

1987

Language:

english

File:

PDF, 2.61 MB

english, 1987

11

Antiviral activity of antisense oligonucleotides linked to poly(L-lysine):targets on genomic RNA and/or mRNA of Vesicular Stomatitis Virus

Leonetti, Jean-Paul, Degols, Genevieve, Milhaud, Pierre, Gagnor, Corinne, Lemaitre, Marc, Lebleu, Bernard

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

1989

Language:

english

File:

PDF, 344 KB

english, 1989

12

Cell penetrating peptides: overview and applications to the delivery of oligonucleotides

F. Said Hassane, A. F. Saleh, R. Abes, M. J. Gait, Bernard Lebleu

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

13

Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugates

Saïd Abes, Donna Williams, Paul Prevot, Alain Thierry, Michael J. Gait, Bernard Lebleu

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 720 KB

english, 2006

14

Comparison of basic peptides- and lipid-based strategies for the delivery of splice correcting oligonucleotides

Alain R. Thierry, Said Abes, Sarah Resina, Adrian Travo, Jean Philippe Richard, Paul Prevot, Bernard Lebleu

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2006

Language:

english

File:

PDF, 445 KB

english, 2006

15

Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake

Leonetti, Jean Paul, Degols, Genevieve, Lebleu, Bernard

Journal:

Bioconjugate Chemistry

Year:

1990

Language:

english

File:

PDF, 1.10 MB

english, 1990

16

Phosphorothioate Analogs OF 2-5A: Activation / Inhibition of Rnase L and Inhibition of HIV-1 Reverse Transcriftase

Suhadolnik, Robert, Lebleu, Bernard, Pfleiderer, Wolfgang, Charubala, Ramamurthy, Montefiori, David, Mitchell, William, Sobol, Robert, Li, Shi Wu, Kariko, Katalin, Reichenbach, Nancy

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

1989

Language:

english

File:

PDF, 409 KB

english, 1989

17

Regeneration of enzyme activity after Western blot: Activation of RNase L by 2-5A on filter— Importance for its detection

Tamim Salehzada, Michelle Silhol, Bernard Lebleu, Catherine Bisbal

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 1.44 MB

english, 1991

18

Oligonucléotides antisens en chimiothérapie antivirale : problèmes et perspectives d'utilisation

Ian Robbins, Lionel Bastide, Bernard Lebleu

Journal:

Revue Française des Laboratoires

Year:

1998

File:

PDF, 1.88 MB

1998

19

Imporved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

Bongartz, Jean-Pierre, Aubertain, Anne-Marie, Milhaud, Pierre G., Lebleu, Bernard

Journal:

Nucleic Acids Research

Year:

1994

Language:

english

File:

PDF, 2.18 MB

english, 1994

20

Antibody-Targeted Lipsomes Containing Oligodeoxyribonucleotides Complementary to Viral RNA Selectively Inhibit Viral Replication

Jean-Paul Leonetti, Patrick Machy, Genevieve Degols, Bernard Lebleu and Lee Leserman

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 834 KB

english, 1990

21

Preface

Gillian Barratt, Didier Betbeder, Bernard Lebleu

Journal:

International Journal of Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 76 KB

english, 2009

22

Delivering information-rich drugs -prospects and challenges

Journal:

Trends in Biotechnology

Year:

1996

Language:

english

File:

PDF, 287 KB

english, 1996

23

Synthesis and Splice-Redirecting Activity of Branched, Arginine-Rich Peptide Dendrimer Conjugates of Peptide Nucleic Acid Oligonucleotides

Saleh, Amer F., Arzumanov, Andrey, Abes, Rachida, Owen, David, Lebleu, Bernard, Gait, Michael J.

Journal:

Bioconjugate Chemistry

Year:

2010

Language:

english

File:

PDF, 1.94 MB

english, 2010

24

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency

Yin, HaiFang, Boisguerin, Prisca, Moulton, Hong M, Betts, Corinne, Seow, Yiqi, Boutilier, Jordan, Wang, Qingsong, Walsh, Anthony, Lebleu, Bernard, Wood, Matthew JA

Journal:

Molecular Therapy — Nucleic Acids

Year:

2013

Language:

english

File:

PDF, 931 KB

english, 2013

25

Delivery of therapeutic oligonucleotides with cell penetrating peptides

Boisguérin, Prisca, Deshayes, Sébastien, Gait, Michael J., O'Donovan, Liz, Godfrey, Caroline, Betts, Corinne A., Wood, Matthew J.A., Lebleu, Bernard

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 1.86 MB

english, 2015

26

Sequence-Specific Inhibition of Human Immunodeficiency Virus (HIV) Reverse Transcription by Antisense Oligonucleotides: Comparative Study in Cell-Free Assays and in HIV-Infected Cells

Bruno Bordier, Maritta Perala-Heape, Genevieve Degols, Bernard Lebleu, Simon Litvak, Leila Sarih-Cottin and Claude Helene

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

27

The 2–5A/RNase L/RNase L Inhibitor (RNI) Pathway Regulates Mitochondrial mRNAs Stability in Interferon α-treated H9 Cells

Le Roy, Florence, Bisbal, Catherine, Silhol, Michelle, Martinand, Camille, Lebleu, Bernard, Salehzada, Tamim

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 642 KB

english, 2001

28

4981957 Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini

Bernard Lebleu, Bernard Bayard

Journal:

International Journal of Biochemistry

Year:

1991

Language:

english

File:

PDF, 107 KB

english, 1991

29

Structure–activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1 Tat protein

Eric Vivès, Claude Granier, Paul Prevot, Bernard Lebleu

Journal:

International Journal of Peptide Research and Therapeutics

Year:

1997

Language:

english

File:

PDF, 1.41 MB

english, 1997

30

Differential effects of various double-stranded RNAs on protein synthesis in rabbit reticulocyte lysates

Content, Jean, Lebleu, Bernard, De Clercq, Erik

Journal:

Year:

1978

Language:

english

File:

PDF, 888 KB

english, 1978

31

Antiviral activity and possible mechanisms of action of oligonucleotides-poly(L-lysine) conjugates targeted to vesicular stomatitis virus mRNA and genomic RNA

Degols, Geneviève, Leonetti, Jean-paul, Gagnor, Corinne, Lemaitre, Marc, Lebleu, Bernard

Journal:

Nucleic Acids Research

Year:

1989

Language:

english

File:

PDF, 12.78 MB

english, 1989

32

Impact of the Guanidinium Group on Hybridization and Cellular Uptake of Cationic Oligonucleotides

Gaëlle Deglane, Saïd Abes, Thibaut Michel, Paul Prévot, Eric Vives, Françoise Debart, Ivan Barvik, Bernard Lebleu, Jean-Jacques Vasseur

Journal:

Year:

2006

Language:

english

File:

PDF, 762 KB

english, 2006

33

Switching on transgene expression by correcting aberrant splicing using multi-targeting steric-blocking oligonucleotides

Sarah Resina, Ryszard Kole, Adrian Travo, Bernard Lebleu, Alain R. Thierry

Journal:

The Journal of Gene Medicine

Year:

2007

Language:

english

File:

PDF, 392 KB

english, 2007

34

Modulation of nucleic acid information processing by PNAs: potential use in anti-viral therapeutics

Lionel Bastide, Bernard Lebleu, Ian Robbins

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 1.32 MB

english, 2003

35

Cell penetrating peptide conjugates of steric block oligonucleotides

Bernard Lebleu, Hong M. Moulton, Rachida Abes, Gabriela D. Ivanova, Said Abes, David A. Stein, Patrick L. Iversen, Andrey A. Arzumanov, Michael J. Gait

Journal:

Advanced Drug Delivery Reviews

Year:

2008

Language:

english

File:

PDF, 467 KB

english, 2008

36

Antiviral activity in L1210 cells of liposome-encapsulated (2′-5′)oligo(adenylate) analogues

Bernard BAYARD, Lee D. LESERMAN, Catherine BISBAL, Bernard LEBLEU

Journal:

Year:

1985

Language:

english

File:

PDF, 681 KB

english, 1985

37

Blocks in Elongation and Initiation of Protein Synthesis Induced by Interferon Treatment in Mouse L Cells

Jean CONTENT, Uri NUDEL, Asher ZILBERSTEIN, Hanna BERISSI, Michel REVEL, Bernard LEBLEU

Journal:

Year:

1975

Language:

english

File:

PDF, 947 KB

english, 1975

38

cDNA cloning and expression analysis of the murine ribonuclease L inhibitor

Amélie Benoit De Coignac, Catherine Bisbal, Bernard Lebleu, Tamim Salehzada

Journal:

Year:

1998

Language:

english

File:

PDF, 927 KB

english, 1998

39

Poly(L-Lysine)-Conjugated Oligonucleotides Promote Sequence-Specific Inhibition of Acute HIV-1 Infection

DEGOLS, GENEVIÈVE, LEONETTI, JEAN-PAUL, BENKIRANE, MONSEF, DEVAUX, CHRISTIAN, LEBLEU, BERNARD

Journal:

Antisense Research and Development

Year:

1992

Language:

english

File:

PDF, 1.71 MB

english, 1992

40

Editorial (Hot Topic: Cell Penetrating Peptides as Delivery Vectors for Biomolecules)

Lebleu, Bernard

Journal:

Current Pharmaceutical Design

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

41

Free and Liposome-Encapsulated Double-Stranded RNAs as Inducers of Interferon, Interleukin-6, and Cellular Toxicity

MILHAUD, PIERRE G., MACHY, PATRICK, COLOTE, SOUDHIR, LEBLEU, BERNARD, LESERMAN, LEE

Journal:

Journal of Interferon Research

Year:

1991

Language:

english

File:

PDF, 613 KB

english, 1991

42

A Short Phosphodiester Window Is Sufficient to Direct RNase H-Dependent RNA Cleavage by Antisense Peptide Nucleic Acid

MALCHÉRE, CHARLOTTE, VERHEIJEN, JEROEN, VAN DER LAAN, SANDER, BASTIDE, LIONEL, VAN BOOM, JACQUES, LEBLEU, BERNARD, ROBBINS, IAN

Journal:

Antisense and Nucleic Acid Drug Development

Year:

2000

Language:

english

File:

PDF, 5.61 MB

english, 2000

43

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents

Saïd Abes, Hong M. Moulton, Philippe Clair, Paul Prevot, Derek S. Youngblood, Rebecca P. Wu, Patrick L. Iversen, Bernard Lebleu

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 857 KB

english, 2006

44

Subcellular distribution of 2′,5′-oligoadenylate synthetase in differentiating Friend leukemia cells

Nadir Mechti, Elisabetta Affabris, Gianna Romeo, Bernard Lebleu

Journal:

Differentiation

Year:

1985

Language:

english

File:

PDF, 361 KB

english, 1985

45

Specific Antiviral Activity of a Poly(L-lysine)-Conjugated Oligodeoxyribonucleotide Sequence Complementary to Vesicular Stomatitis Virus N Protein mRNA Initiation Site

Marc Lemaitre, Bernard Bayard and Bernard Lebleu

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 868 KB

english, 1987

46

Activation of ribonuclease L by (2'-5')(A)4-poly(L)-lysine) conjugates in intact cells

Bayard, Bernard, Bisbal, Catherine, Lebleu, Bernard

Journal:

Year:

1986

Language:

english

File:

PDF, 1.98 MB

english, 1986

47

Chemical Modifications to Improve the Cellular Uptake of Oligonucleotides

Debart, Francoise, Abes, Said, Deglane, Gaelle, Moulton, Hong, Clair, Philippe, Gait, Michael, Vasseur, Jean-Jacques, Lebleu, Bernard

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 385 KB

english, 2007

48

Plasma-deposited nanocomposite polymer-silver coating against Escherichia coli and Staphylococcus aureus: Antibacterial properties and ageing

Allion-Maurer, Audrey, Saulou-Bérion, Claire, Briandet, Romain, Zanna, Sandrine, Lebleu, Nathalie, Marcus, Philippe, Raynaud, Patrice, Despax, Bernard, Mercier-Bonin, Muriel

Journal:

Surface and Coatings Technology

Year:

2015

Language:

english

File:

PDF, 1.72 MB

english, 2015

49

Intracellular Distribution of Microinjected Antisense Oligonucleotides

Jean Paul Leonetti, Nadir Mechti, Genevieve Degols, Corinne Gagnor and Bernard Lebleu

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.21 MB

english, 1991

50

Context Dependent Effects of Chimeric Peptide Morpholino Conjugates Contribute to Dystrophin Exon-skipping Efficiency

Yin, HaiFang, Boisguerin, Prisca, Moulton, Hong M., Betts, Corinne, Seow, Yiqi, Boutilier, Jordan, Wang, Qingsong, Walsh, Anthony, Lebleu, Bernard, Wood, Matthew J.A.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 231 KB

2020

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